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  • What is APOL1-mediated kidney disease?
  • About the investigational study drug
  • About the AMPLITUDE clinical research study and FAQs
  • Can I take part in the AMPLITUDE clinical research study?
  • Contact

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Are you between 18–60 years old?
Do you identify as someone of African ancestry? This may include Black, Caribbean, African American, Sub-Saharan African, or Latino (defined as a person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin).
Have you been diagnosed with chronic kidney disease?
Have you been diagnosed with hypertensive kidney disease?
Have you been diagnosed with nephrotic syndrome?
Have you been diagnosed with focal segmental glomerulosclerosis (FSGS) syndrome?
Have you, or anyone in your family, ever been told that you, or they, have an APOL1 genetic variant?
Have you been diagnosed with diabetes?
Are you currently pregnant or breastfeeding, or are you planning to become pregnant or to breastfeed in the next 4 years?
Are you willing to get a genetic test to understand more about your kidney health?

Based on the answers you have given, you may be eligible to take part in this clinical research study.

If you would like to join the AMPLITUDE clinical research study, please provide your contact details below to request a call from the study site. The site will contact you to discuss the study further, confirm that you meet all of the requirements to take part, and answer any questions you may have.
Do you want to submit you contact details?

Based on the answers you have given, it appears you do not meet the requirements for taking part in this clinical research study.

If the study requirements change, a representative from the study team can contact you to discuss your interest and eligibility.
If you would like to be contacted for future opportunities, please fill out the following contact form.
Please fill in your details below if you would like to be contacted in the event the study requirements change or for future Vertex clinical research study opportunities.
Do you want to submit you contact details?
Name(Required)
What is the best way to contact you?
Do you provide permission for a research site to leave a voice message if you are unavailable?
Please select from the options below to determine how long we can keep your information, and whether we can contact you at a later date if there is a change in the AMPLITUDE clinical research study criteria, or if a new clinical research study becomes available.
Please note: We will not send junk or spam email to you; we will contact you only in relation to the AMPLITUDE clinical research study and/or future Vertex clinical research studies based on your selected criteria above. Email addresses are not used for any other purpose without your consent.

By clicking “Continue,” you are agreeing to let us keep your information in the event the research criteria change or in the event a new clinical research study becomes available and to share the information you have provided with a research site, as well as to have a research site contact you.
Please note: COUCH Health or the research site will not send junk or spam email to you; you will be contacted only in relation to the AMPLITUDE clinical research study and/or future Vertex studies based on your selected criteria above. Email addresses are not used for any other purpose without your consent.

By clicking continue, you are agreeing to let COUCH Health share the information you have provided with a research site, as well as to have a research site contact you.
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Please note that "We Are COUCH Ltd" (trading as COUCH Health) are acting as a data processor on behalf of Vertex when collecting your data as part of the pre-screening process for the AMPLITUDE study. The pre-screener information you submit will not be shared with Vertex. You will have the option to delete the information after you complete the pre-screening process.

In the event you may be eligible for this study, you will have the option to provide contact information and allow COUCH Health to forward your information to a research site. In the event you are not eligible for this study, you will have the option to provide contact information to be contacted if the eligibility criteria change for the AMPLITUDE study or for future Vertex studies.

Privacy Information for Residents of California: We Are COUCH Ltd (trading as COUCH Health) is a service provider to the sponsor of the AMPLITUDE study, Vertex, when collecting data as part of this pre-screening questionnaire. The categories of information collected via this questionnaire include: information about your health and ancestry (to determine eligibility) as well as contact information (in the event you choose to share it).

The information will be used only to determine whether you are eligible for this research study and, if you consent, to inform you of potential Vertex research studies in the future. If your answers to the questionnaire indicate you may be eligible for this study and you elect to share your contact information, COUCH Health will share your information with a research site, which will contact you to do a full screening. Even if you are not found to be eligible for this study, you will have the option for COUCH Health to keep your information on file for a period of time that you elect and notify you of future Vertex studies.

For a fuller description of Vertex’s privacy practices and of your privacy rights, please see Vertex’s Privacy Notice at https://www.vrtx.com/english-privacy-us-residents/.

If you have a question or want to exercise your privacy rights, please contact COUCH Health at amplitude@couchhealth.co as Vertex will not receive any information about you from this website.